INDICATIONS     CONTRA-INDICATIONS     DOSAGE     SIDE-EFFECTS     PREGNANCY     OVERDOSE     IDENTIFICATION     PATIENT INFORMATION
YOMESAN®

SCHEDULING STATUS:
Not scheduled

PROPRIETARY NAME
(and dosage form):

YOMESAN^®
Tablets

COMPOSITION:
Each tablet contains 500 mg niclosamide.

PHARMACOLOGICAL CLASSIFICATION:
A. 12 Anthelmintics.

PHARMACOLOGICAL ACTION:
Yomesan expels the cestodes from the intestine. No effect can therefore be expected in cysticercosis and echinococcosis due to cestode larvae (cysticerci) lodging in extra-intestinal tissue.

INDICATIONS:
Infections with:
Taenia saginata (beef tapeworm)
Taenia solium (pork tapeworm)
Diphyllobothrium latum (fish tapeworm)
Hymenolepis nana (dwarf tapeworm).

CONTRA-INDICATIONS:
Hypersensitivity to niclosamide.
Yomesan may be given safely after the first three months of pregnancy, and to patients with liver, biliary and kidney diseases.

DOSAGE AND DIRECTIONS FOR USE:
Yomesan tablets are taken after breakfast. It is very important that the palatable tablets are thoroughly chewed and then washed down with a little water. The tablets may also be taken disintegrated in a little water. For small children it is advisable to grind the tablets as finely as possible and mix the powder with a little water. If constipated, thorough cleansing of the bowels is necessary before treatment. Dietetic measures are not necessary.
In infestation with beef tapeworm (T. saginata), pork tapeworm (T. solium) and fish tapeworm (D. latum) one single dose is sufficient.

Adults and children from 6 years upwards	-	4 tablets
Children from 2-6 years	-	2 tablets
Children under 2 years	-	1 tablet

A drastic saline purge (e.g. sodium sulphate, magnesium sulphate), given two hours after the Yomesan dose should ensure a rapid and complete expulsion of the worm. Without purgation, the parasite is excreted in pieces during the next few days. In the case of Taenia solium, a drastic purge is imperative. For infections with the dwarf tapeworm (H. nana), the following treatment for 7 days is recommended:
First day:

Adults and children from 6 years upwards	-	4 tablets
Children from 2-6 years	-	2 tablets
Children under 2 years	-	1 tablet

For another six days:

Adults and children from 6 years upwards	-	2 tablets daily
Children from 2-6 years	-	1 tablet daily
Children under 2 years	-	½ tablet daily

CAUTION : DO NOT REMOVE FROM FOIL UNTIL IMMEDIATELY BEFORE ADMINISTRATION

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Yomesan may cause disturbances of the gastro-intestinal tract such as nausea, retching and abdominal pain. No alcohol should be taken during treatment.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
According to available evidence, the active substance of Yomesan, niclosamide is only slightly absorbed, so that toxic effects are not expected. Should a patient have taken a marked overdosage, for safety reasons the usual therapeutic measures for the treatment of poisoning should be applied (gastric lavage, symptomatic therapy).

IDENTIFICATION:
A creamy-yellow vanilla flavoured tablet with the Bayer cross on one side and FE on the other side.

PRESENTATION:
Packs of 4 tablets.
Packs of 100 tablets.

STORAGE INSTRUCTIONS:
Keep out of reach of children. Store below 25°C.

REFERENCE NO.:
H890 (Act 101/1965).

NAME AND BUSINESS ADDRESS OF APPLICANT:
Bayer (Pty) Ltd
Reg. No. 68/11192/07
Wrench Road        Isando        1600

DATE OF PUBLICATION OF THIS PACKAGE INSERT:
February 1988

^® = Registered trade mark of Bayer, Germany

Updated on this site: February 2003
Source: Pharmaceutical Industry
SAEPI HOME PAGE      TRADE NAME INDEX      GENERIC NAME INDEX      FEEDBACK
Information presented by Malahyde Information Systems © Copyright 1996-2003